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四川首富又要敲钟了

陈佳 周佳丽 2026-08-11 08:43
陈佳 周佳丽 2026/08/11 08:43

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本文核心介绍了四川企业家朱义创办百利天恒、冲击A+H上市的创业经历,同时梳理了当前国内企业赴港A+H上市的整体行情。

1. 朱义原本是大学老师,90年代下海赚得第一桶金后回成都创办百利天恒,先做仿制药做到西南地区龙头,随后预判仿制药利润会变薄,2010年all in创新药,走出了以成熟业务养研发的差异化路线,最终凭借84亿美元的ADC药合作交易一战成名,市值突破千亿,朱义也成为四川首富。

2. 当前A+H上市潮正盛,硬科技成为主力,同时也存在明显分化,不少缺乏增长故事的企业出现上市破发,风险不容忽视。

本文给计划布局创新、推进全球化发展的品牌企业提供了多维度的参考干货。

1. 行业趋势层面,创新是品牌长期发展的核心出路,百利天恒创始人朱义早在2010年就判断仿制药未来利润微薄,果断将仿制药赚得的利润全部投入创新药研发,最终抓住ADC赛道机遇实现千亿市值跨越,对各类品牌的研发方向有参考意义。

2. 路径选择层面,品牌转型创新可以走“以旧养新”的差异化路线,用成熟业务的利润反哺研发,不必过度依赖早期外部融资,降低转型风险,百利天恒上市前仅两轮外部融资就是成功案例。

3. 全球化布局层面,A+H上市是对接国际资本、推进全球业务的有效路径,但也要警惕上市分化带来的破发风险,只有拥有清晰增长故事的硬科技、创新品牌更容易获得资本认可。

本文披露了当前国内企业赴港IPO的最新行情,给有全球化布局、融资需求的经营者提供了机会和风险提示。

1. 当前机会层面,A+H上市已经形成风口,2026年上半年就有24家A股公司赴港上市,融资规模占到同期中企港股IPO融资额的近六成,硬科技、创新药成为本轮上市的主力,相关赛道的企业更容易获得资本关注度。

2. 价值层面,企业南下港股上市,核心价值是对接国际资本,能为企业全球化研发、海外产能扩张储备充足资金,适配当下企业产业链全球化的发展需求。

3. 风险提示层面,当前港股IPO分化十分明显,缺乏清晰增长故事的企业容易出现认购冷淡、下调发行价甚至撤回申请的情况,已有多家企业上市首日破发,计划赴港上市的经营者需要提前做好准备。

本文给医药制造工厂以及计划转型升级的生产企业提供了明确的方向参考。

1. 产品方向层面,传统仿制药未来利润会越来越薄,创新品类是制造业长期发展的核心机会,提前布局研发才能抓住行业红利,百利天恒就是从区域仿制药小龙头,通过提前布局创新ADC药,成长为千亿市值药企的典型案例。

2. 商业机会层面,当前国内优质制造尤其是硬科技领域的制造企业,可以通过A+H上市对接国际资本,获得充足资金推进研发和全球化布局,是当前不错的融资机会。

3. 转型路径层面,中小制造企业转型创新可以参考“以旧养新”模式,用现有成熟业务的利润反哺创新研发,不需要过度依赖外部融资,能够大幅降低转型过程中的资金压力和风险。

本文梳理了当前创新药、硬科技领域企业的最新发展动向,给为企业提供资本、研发、上市相关服务的服务商指明了业务方向。

1. 行业发展趋势层面,当前A+H上市已经成为头部A股硬科技、创新药企业的核心需求,2026年上半年就有24家A股企业赴港IPO,硬科技已经接过消费、传统制造的接力棒成为上市主力,对应的上市辅导、资本对接等服务需求大幅增长。

2. 客户核心痛点层面,创新企业进入研发后期后资金需求大幅提升,国内企业推进全球化布局也需要稳定的国际资本对接渠道,多数企业缺乏相关资源和经验。

3. 业务方向层面,服务商可以针对性布局A+H上市相关服务,聚焦硬科技、创新药赛道,为企业提供上市辅导、国际资本对接等配套服务,抓住本轮行业增长的机会。

本文披露了当前实体企业对资本平台的最新需求,以及港股IPO市场的最新特征,给资本平台的运营和招商提供了参考。

1. 企业需求层面,随着国内头部企业的研发、产能、客户逐步全球化,企业需要对接国际资本的平台支撑,A+H上市成为头部企业的主流选择,平台需要针对性优化服务适配这类头部企业的需求。

2. 招商方向层面,当前A+H上市中头部硬科技、创新药企业IPO关注度高、融资规模大,是港股IPO市场的核心优质资源,平台招商可以侧重倾斜这类赛道的优质企业,提升平台融资规模和影响力。

3. 风险规避层面,当前A+H上市分化明显,缺乏增长故事的企业容易出现破发,平台要做好企业资质筛选,优化配套服务,避免大量破发影响平台整体声誉,维护市场稳定。

本文呈现了国内创新药产业发展和资本市场的最新动向,给产业和资本市场研究者提供了新的研究方向和素材。

1. 产业层面,国内创新药领域出现了区别于传统海归创业拿融资的新模式,即“以旧养新”模式,用成熟仿制药业务的利润反哺创新研发,百利天恒依靠该模式成长为千亿市值创新药企,这种本土化创新商业模式值得深入研究。

2. 资本市场层面,当前A+H上市潮兴起,硬科技成为本轮上市的主力,2026年上半年24家A股企业赴港上市,融资额占同期中企港股IPO近六成,头部企业集体南下对接国际资本成为产业和资本市场的新动向。

3. 研究方向层面,当前A+H上市分化明显,破发风险凸显,如何完善国内多层次资本市场建设,帮助国内优质创新企业更好对接国际资本,控制上市风险,是值得深入研究的新问题。

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Quick Summary

This article centers on the entrepreneurial journey of Sichuan-based businessman Zhu Yi, who founded Bilin Pharmaceutical and is pursuing an A+H dual listing. It also outlines the current landscape of Chinese companies pursuing A+H listings in Hong Kong.

1. Zhu, a former university lecturer, entered business in the 1990s. After earning his first fortune, he returned to Chengdu to found Bilin, which first grew into a regional leader in generic drugs. Anticipating that generic drug margins would shrink, Zhu pivoted to a full commitment to innovative drug development in 2010, adopting a differentiated "fund R&D via mature business" model. The company rose to prominence with an $8.4 billion ADC drug collaboration deal, pushing its market cap above 100 billion yuan and making Zhu the richest person in Sichuan.

2. A+H listings are currently booming, with hard tech companies leading the trend. However, the market is sharply divided: many companies lacking a clear growth narrative have seen their shares drop below IPO price on debut, and the downside risks cannot be ignored.

This article provides multi-dimensional insights for brand companies planning to pursue innovation and expand globally.

1. In terms of industry trend, innovation is the core path for long-term brand growth. Bilin founder Zhu Yi predicted thin margins for generics as early as 2010, and reinvested all profits from generic drug sales into innovative R&D, ultimately seizing the opportunity in the ADC track to reach a 100 billion yuan market capitalization. This experience offers valuable reference for R&D strategy planning across all types of brands.

2. In terms of transformation path, brands can adopt the differentiated "fund new innovation via mature legacy business" model, using profits from established operations to fund R&D instead of over-relying on early-stage external financing, which reduces transformation risk. Bilin’s success with only two rounds of external financing before listing serves as a strong case study.

3. In terms of global expansion, an A+H listing is an effective path to access international capital and advance global operations. However, companies must be wary of the IPO breakout risk amid the current market divergence. Only hard tech and innovative brands with clear growth stories are more likely to win capital recognition.

This article discloses the latest trends of Chinese companies pursuing IPOs in Hong Kong, and outlines both opportunities and risks for operators with global expansion and financing needs.

1. On the opportunity side: A+H listings have become a major trend. In the first half of 2026 alone, 24 A-share listed companies conducted secondary listings in Hong Kong, accounting for nearly 60% of total IPO fundraising by Chinese companies on the Hong Kong stock market in the period. Hard tech and innovative drug companies lead this wave of listings, and companies in these sectors are far more likely to attract capital attention.

2. On the value side: The core benefit of a Hong Kong listing is access to international capital, which allows companies to reserve sufficient funds for global R&D and overseas capacity expansion, matching the current demand for globalized industrial chains among Chinese enterprises.

3. On the risk side: The Hong Kong IPO market is currently sharply divided. Companies without a clear growth story often face weak subscription, forced IPO price cuts, or even full withdrawal of applications. Multiple firms have already broken below their IPO price on debut, so operators planning a Hong Kong listing need to make thorough preparations in advance.

This article offers clear directional guidance for pharmaceutical manufacturing factories and manufacturing enterprises planning transformation and upgrading.

1. In terms of product strategy: Profit margins for traditional generic drugs will continue to narrow, and innovative product categories are the core opportunity for long-term development in manufacturing. Only companies that lay out R&D early can capture industry dividends. Bilin is a representative example: it grew from a small regional generic drug leader to a 100 billion yuan market cap pharmaceutical firm through early布局 in innovative ADC drugs.

2. In terms of business opportunities: Currently, high-quality domestic manufacturing enterprises, especially those in the hard tech sector, can access international capital via A+H listings to secure sufficient funding for R&D and global expansion, making this a compelling financing opportunity at present.

3. In terms of transformation path: Small and medium-sized manufacturing enterprises pursuing innovation can follow the "fund new innovation via mature business" model, reinvesting profits from existing established operations into innovative R&D. This approach avoids over-reliance on external financing and greatly reduces capital pressure and risk during transformation.

This article summarizes the latest development trends of innovative drug and hard tech companies, and clarifies business direction for service providers that offer capital, R&D and listing-related services to enterprises.

1. In terms of industry trend: A+H listing has become a core demand for leading A-share listed hard tech and innovative drug companies. In the first half of 2026 alone, 24 A-share companies conducted IPOs in Hong Kong, and hard tech has replaced consumer and traditional manufacturing as the main driving force of new listings. This has driven significant growth in demand for related services including listing counseling and capital connection.

2. In terms of client core pain points: As innovative enterprises enter the late stage of R&D, their capital demand rises sharply. At the same time, Chinese enterprises expanding globally need stable channels to connect with international capital, while most firms lack relevant resources and experience.

3. In terms of business direction: Service providers can build targeted service offerings for A+H listings, focus on the hard tech and innovative drug sectors, and provide supporting services such as listing counseling and international capital connection to capture growth opportunities from this industry wave.

This article discloses the latest demand from physical enterprises for capital platforms and the latest characteristics of the Hong Kong IPO market, providing reference for the operation and investment promotion of capital platforms.

1. In terms of enterprise demand: As R&D, production capacity and customer bases of leading Chinese enterprises gradually globalize, companies need platform support to connect with international capital, and A+H listing has become the mainstream choice for leading firms. Platforms need to optimize their targeted services to meet the demand of these leading enterprises.

2. In terms of investment promotion direction: Leading hard tech and innovative drug companies pursuing A+H listings attract high market attention and raise large amounts of capital, making them core high-quality resources for the Hong Kong IPO market. Platforms can prioritize attracting high-quality companies from these sectors to boost their own fundraising scale and influence.

3. In terms of risk mitigation: The A+H listing market is sharply divided, and companies without strong growth stories face high breakout risk. Platforms need to conduct strict qualification screening, optimize supporting services, avoid damage to overall platform reputation from widespread IPO breakouts, and maintain market stability.

This article presents the latest trends in China’s innovative drug industry and capital market, providing new research directions and materials for industry and capital market researchers.

1. On the industry side: A new localized innovative business model, "grow new innovation via mature legacy business", has emerged in China’s innovative drug sector, distinct from the traditional returnee founder VC-backed model. In this model, profits from mature generic drug operations fund innovative R&D. Bilin grew into a 100 billion yuan innovative pharmaceutical company via this approach, making this localized innovative business model worthy of in-depth research.

2. On the capital market side: An A+H listing boom is currently underway, with hard tech leading the new wave of listings. In the first half of 2026, 24 A-share companies listed in Hong Kong, accounting for nearly 60% of total IPO fundraising by Chinese companies on the Hong Kong bourse in the period. The collective move of leading Chinese enterprises to access international capital via Hong Kong is a new trend for both industry and capital markets.

3. On future research directions: The A+H market is sharply divided, and breakout risks are growing. How to improve China’s multi-layer capital market system, help high-quality domestic innovative enterprises better connect with international capital, and control listing risks is a new issue worthy of in-depth research.

Disclaimer: The "Quick Summary" content is entirely generated by AI. Please exercise discretion when interpreting the information. For issues or corrections, please email run@ebrun.com .

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药王赴港IPO了。

投资界获悉,四川百利天恒药业股份有限公司(简称:百利天恒)已向港交所主板递交上市申请,正式冲击“A+H”上市。

始于成都,百利天恒掌门人是四川企业家朱义。从四川大学到复旦大学,他几经创业后带着积蓄于1996年成立百利天恒。2023年公司登陆科创板IPO后,他凭借一笔现象级License-out掀起暴涨行情,缔造A股又一千亿药企。如此,身后的朱义成为四川新晋首富。

由此望去,今年A+H上市潮浩浩荡荡。

大学老师下海创业,干出1300亿

故事要从创始人朱义说起。

1963年,朱义出生于四川南充,本科就读于四川大学无线电专业,后来进入复旦大学攻读生物学硕士,毕业后在华西医科大学(现称四川大学华西医学中心)微生物学与免疫学教研室任教。这原本是一条安稳的学术道路。但90年代高校科研经费紧张、硬件简陋,前沿研究处处受限。朱义心里清楚:想做好药,得先有钱。

1990年,他离开高校,先是进入四川省科委医药公司做研发,后来揣着300块钱独闯广西北海,从外贸和房地产挣到了第一桶金。“赚了钱还是想回制药行,这是老本行,更是牵挂。”终于在1996年,朱义回到成都温江,创办了百利药业(后更名百利天恒)。

百利药业从仿制药和中成药起步,第一款重要产品利巴韦林颗粒“新博林”,一度占据同品类全国销量第一的位置。靠着它,百利药业成为西南地区仿制药领域的小龙头。

但朱义没有停留在这门安稳的生意上。他的判断是:“世界上只有两种药:创新药和其他。仿制药未来利润薄如刀片。”2010年,百利天恒开始转向创新药,把仿制药赚来的钱,几乎全部投了进去。

和当时大多数海归团队拿融资、讲故事的路径不同,朱义走的是“以旧养新”路线:用成熟业务养活研发,用海外平台搭建管线。2014年,他在美国西雅图设立了SystImmune,开始对抗肿瘤ADC分子BL-B01D1长达十年的研究。

在那一轮创新药投资热潮中,百利天恒并不起眼。直到2017年前后,奥博资本和德福资本先后入局,这也是公司上市前仅有的两笔外部融资。

2023年1月,百利天恒登陆科创板。按照发行价计算,百利天恒彼时发行市值约99亿元。在科创板一众创新药企中,它不算亮眼。

暴涨一幕,四川新晋首

转机很快出现。

科创板上市不到半年,美国临肿瘤学会(ASCO)的年会上,百利天恒公布BL-B01D1数据,引发轰动,全球前十大MNC中有八家递来了橄榄枝。此后半年,SystImmune与全球前20的制药公司“都谈过至少一遍”,包括BMS(百时美施贵宝)。

外界没有想到,朱义等来的会是一笔84亿美元的交易,刷新了当时全球ADC单药交易纪录——2023年12月,百利天恒全资子公司SystImmune与BMS签署独家许可与合作协议,共同开发双抗ADC药物BL-B01D1。

一家成都药企第一次以共同开发者的身份,与全球制药巨头坐到同一张桌子前。消息迅速传遍市场,此前籍籍无名的科创板药企百利天恒,骤然站到聚光灯下,市场随之震动——12月12日当天,百利天恒股价开盘即涨停20%,创下历史新高,市值突破500亿元。

朱义后来在媒体采访中复盘这笔交易,感慨成功背后离不开中国多层次资本市场建设的助力:2023年科创板上市,他融到9.9亿元,“科创板五套标准全为创新企业量身定制,这笔钱让我们把BL-B01D1的临床样本量扩大到800多个中国患者——没有这些数据,根本没法和跨国公司谈。”

一笔BD交易,百利天恒业绩开始暴涨。2024年,百利天恒实现营业收入58.23亿元,同比增幅高达936.31%;归母净利润37.08亿元,一举扭亏为盈。随之而来是股价飙涨,到了2025年9月,百利天恒市值一度超过1500亿元。相比24.70元的发行价,最高股价涨幅超过15倍。

招股书显示,掌门人朱义直接持有百利天恒已发行股份总数的约72%,伴随股价大涨,他的身家也水涨船高。2026年《胡润全球富豪榜》中,朱义以980亿元财富二次登顶四川首富。但对于“首富”的名号,朱义却是格外清醒,他曾在媒体采访中将之总结为“纸上财富带来的虚名”。

原因不难理解,创新药进入后期临床后,真正烧钱的阶段才刚刚开始。为了全球化募资,2025年百利天恒启动H股上市,原计划11月挂牌,却在最后关头按下暂缓键。

如今,随着核心产品宜泽康获批上市,全球首款双特异性ADC药物终于摆上药房货架。百利天恒调整姿势,再度冲刺港股。也许很快,这位四川首富要IPO敲锣了。

千亿IPO排队,惕破

此时此刻,A+H上市潮正在涌来。

清科研究中心数据显示,2026年上半年已有24家A股公司赴港上市,融资规模约956.51亿元人民币,占同期中企港股IPO融资额近六成。而2025年全年,这一数字是19家。一批A股巨头南下,拿走了港股IPO市场大半的资金。

长长的队伍里,硬科技正接过消费、传统制造的接力棒,成为本轮A+H上市的主力。

最早掀起声势的是宁德时代。2025年5月,这家动力电池巨头登陆港交所,上市时市值达到1.3万亿港元,一度成为当年全球规模最大的IPO。三天后,医药“一哥”恒瑞医药也在香港敲钟。

进入2026年,潮水愈发汹涌。上半年港股募资额排名靠前的胜宏科技、牧原股份和东鹏饮料,清一色是A+H双重上市。7月,潮汕女掌门带队超4000亿市值的立讯精密,登陆港交所IPO敲锣舞台;月末,市值超万亿的光模块龙头中际旭创也登陆港交所,创下年内港股最大IPO。

队伍还有很长。摩尔线程刚刚宣布启动H股筹备,江波龙、绿联科技也在排队。随着新易盛、天孚通信先后筹划赴港,A股“易中天”有望很快会师香江。

巨头们为何集体南下?

答案并不复杂。当一家中国公司的工厂、客户、研发团队和竞争对手遍布全球,资本平台也需要随之走出去。港股自然成为连接境内产业与国际资本的一座码头:有人从这里把工厂建到欧洲,有人借此推进创新药全球临床,也有人需要为下一代大模型和机器人准备更充足的弹药。

但分化同样明显。头部硬科技公司被争抢,发行规模一再扩大;缺乏增长故事的企业则面临认购冷淡、下调发行价甚至撤回。最近,已有多家A+H上市首日破发。

考验从未停止。

注:文/陈佳 周佳丽,文章来源:投资界(公众号ID:pedaily2012),本文为作者独立观点,不代表亿邦动力立场。

文章来源:投资界

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百利天恒是一家什么公司?

百利天恒是朱义1996年在成都创办的创新药企,前身为百利药业,早期以仿制药、中成药起家,2010年全面转型创新药研发,2023年登陆科创板,核心产品包括全球首款双特异性ADC药物,2025年市值一度突破1500亿元,目前正冲击A+H上市。

朱义为什么能成为四川首富?

朱义是百利天恒实控人,直接持有公司约72%股份,2023年旗下子公司与BMS达成84亿美元ADC药物合作,刷新全球ADC单药交易纪录,带动公司股价较发行价最高涨幅超15倍,2026年他以980亿元身家登顶四川首富。

当前A+H上市的主力赛道有哪些?

2025年以来的A+H上市潮中,硬科技已经取代消费、传统制造成为上市主力,涵盖动力电池、创新药、光模块、高端制造、半导体等赛道,宁德时代、恒瑞医药、中际旭创等龙头企业均已完成A+H上市。

企业选择A+H上市有哪些作用?

A+H上市可搭建连接境内产业与国际资本的平台,适配企业全球化布局需求,可支持企业海外建厂、推进创新药全球临床试验、为前沿技术研发储备充足资金,满足企业全球业务扩张的资本需求。

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